Redheads better adapted for sun-shunning lifestyles

If you’re a redhead and have the misfortune of being made fun of for that, it might be worth pointing out that you’re a wonderful product of evolution!

Fair skin and red hair first appeared around the time people settled in Europe 50,000 years ago and still remains a dominant gene in southern Europeans today, even if they can catch a tan.

Known as V6OL allele, the gene made skin lighter as humans were getting less vitamin D from no longer being in the harsh African sun.

[Source: Daily Mail]



Statins inappropriate in kidney disease

“There is very little benefit to statin drugs for patients in the early stages of kidney disease, and no benefit or possible toxicity for patients in later stages,” said Ali Olyaei, a professor of pharmacotherapy in the College of Pharmacy at Oregon State University, and lead author on the new report.

…The impetus to use statin drugs – some of the most widely prescribed medications in the world to lower cholesterol – is obvious in end-stage kidney disease, because those patients have a mortality rate from coronary heart disease 15 times that of the general population. Unfortunately, evidence shows the drugs do not help prevent mortality in that situation. There is also no proven efficacy of the value of statins in patients using dialysis, researchers said.

[Source: News Medical]

Fat and fit?

Interesting post. In the context of vitamin D, if you’re skinny but deficient, you won’t be healthy. If you’re obese, you’re also likely to be vitamin D deficient due to a) less probable outdoor [and indoor] activity, and b) D trapped in fat reserves.

I watched a Swedish television commercial the other day. It consisted of depicting a slightly portly middle-aged woman winning a range of different Olympic sports. The point of it – I think – was to show that middle-aged women are better than you think at things you didn’t think they could do; an idea that the company behind the commercial – an internet service provider focusing on online gaming – was eager to enforce.

But regardless of the message or the motive behind the commercial, it got me thinking: does being overweight stop you from being a healthy human being? Is what we’ve been told actually true – that being overweight is a sure ticket to heart conditions, diabetes, circulatory problems and all the rest? Or is there something else hidden here? Could we have oversimplified the issue?

Conventional wisdom

There is such a mountain of statistical data showing links…

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High cholesterol safer for women?

In a study of more than 40,000 men and women under the age of 60, men with high cholesterol had more than three times the risk of having a heart attack, compared with women with high cholesterol.

…“We believe that females below 60 years of age may be protected against some of the cardiovascular consequences of having high cholesterol due to female sex hormones such as estrogen,” he said.

…“The use of lifestyle modification and statin therapy is one of the most effective, cost-effective and high-value therapeutic approaches to prevent cardiovascular events and prolong life in men as well as women,” Fonarow said. “Attention to cholesterol levels and other risk factors [emphasis added] remain vital for both men and women.”

If females are protected by oestrogen and yet high cholesterol is said to cause heart disease, the lipid hypothesis is invalidated. Focus should be heavily on other risk factors. Read my book.

[Source: Poughkeepsie Journal]